TY  - JOUR
T1  - Clinical, Pathological and Immunohistochemical Findings in Diarrheic Dogs and Evaluation of Canine Parvoviral and Coronaviral Enteritis
AU - , Mehmet Haligur AU - , Ozlem Ozmen AU - , Kenan Sezer AU - , Sima Sahinduran 
JO  - Journal of Animal and Veterinary Advances
VL  - 8
IS  - 4
SP  - 720
EP  - 725
PY  - 2009
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2009.720.725
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2009.720.725
KW  - Canine coronavirus
KW  -canine parvovirus
KW  -pathology
KW  -immunohistochemistry
KW  -treatment
AB  - The aim of this study is to examine, clinicopathological findings of naturally occurring diarrhea in dogs and correlate clinical sings with pathological findings of canine parvovirus and coronavirus infection. Hematology, biochemistry, pathology and immunohistochemistry were applied. Vomiting and diarrhea were prominent findings in all affected dogs. The critical values for good prognosis in diarrheic dogs were >2x10<SUP>3</SUP> mm<SUP>-3</SUP> total leukocyte count, below 25 mmol L<SUP>-1</SUP> anion gap and >7.36 blood pH at the admission. Diagnosis was made by immunohistochemical examination in died dog’s guts tissue sections. Strong immunopositive reaction were seen in enterocytes, lymphocytes and macrophages in Payer’s patches in both parvovirus and coronavirus cases. Lesions were more severe in dual infection cases. The most important point of the supportive treatment was fluid and electrolyte therapy against to dehydration in all cases and strong relationship was observed in treatment starting time to recovering dehydration and mortality rate.
ER  -