TY - JOUR T1 - The Influence of Polysaccharides from the Roots of Achyranthes bidentata on Biochemical Parameters Related to Oxidative Stress Induced by Exhaustive Exercise of Rats AU - Zhang, Zhuoying AU - Lin, Jinyang JO - Journal of Animal and Veterinary Advances VL - 11 IS - 24 SP - 4693 EP - 4696 PY - 2012 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2012.4693.4696 UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.4693.4696 KW - exhaustive exercise KW -biochemical parameters KW -oxidative stress KW -Achyranthes bidentata KW -Polysaccharides KW -rats AB - The main purpose of this study was to investigate the effects of polysaccharides from the roots of Achyranthes bidentata (ABP) on exhaustive exercise-induced oxidative stress by measuring related biochemical parameters of rats. The animals were randomly divided into four groups (n = 10 in each group): one control group and three ABP administered groups. The control group was given saline solution and the administered groups were given different doses of ABP (50, 100, 200 mg kg-1) by gavage once a day. After 21 days, the rats performed an exhaustive exercise test on a graded treadmill, along with the determination of related oxidative stress parameters. The results showed that ABP could significantly increase Superoxide Dismutase (SOD), Glutathione Peroxidase (GSH-Px) and Catalase (CAT) activities, decrease Malondialdehyde (MDA) contents in muscle of rats which meant that ABP effectively attenuates oxidative stress induced by exhaustive exercise. ER -