TY - JOUR T1 - Multiphysics Modeling for Bone Remodeling Simulation: A Methodological Framework AU - Balaguera, Manuel Ignacio AU - Acuna, Robayo AU - Vivana, Paula AU - Viloria, Amelec AU - Gaitan, Mercedes AU - Lis, Jenny Paola JO - Journal of Engineering and Applied Sciences VL - 12 IS - 11 SP - 2889 EP - 2896 PY - 2017 DA - 2001/08/19 SN - 1816-949x DO - jeasci.2017.2889.2896 UR - https://makhillpublications.co/view-article.php?doi=jeasci.2017.2889.2896 KW - multiphysics modeling KW - multiphysics simulation KW -bone tissue KW -Bone remodeling KW -integrative modeling AB - In the present study an object oriented integrative modeling methodology is proposed for the construction of synthetic, computational models of bone-bone environment system that allow its simulation under in vivo conditions. The analytical mathematical approach to model and study ordinary materials will be outlined, indicating its limitations when dealing with biomaterials in physiological environments. The proposed object oriented integrative modeling will be explained emphasizing its advantages and possibilities. Finally, the architecture of the “in vivo” modeling and simulation software framework is shown, described and explained indicating further work based on this framework. ER -