TY - JOUR T1 - Effect of MAD (Mandibular Advancement Device) on Obstructive Sleep Apnea and Quality of Sleep AU - Kim, Ka-Eun AU - Hwang, Chung-Poong AU - Park, Soon-Kwon AU - Cho, Il-Young JO - Journal of Engineering and Applied Sciences VL - 12 IS - 14 SP - 3616 EP - 3621 PY - 2017 DA - 2001/08/19 SN - 1816-949x DO - jeasci.2017.3616.3621 UR - https://makhillpublications.co/view-article.php?doi=jeasci.2017.3616.3621 KW - MAD KW -obstructive sleep apnea KW -quality of sleep KW -medical institutions KW -complications AB - This study is intended to verify the efficacy of oral airway dilatation using MAD for the treatment of sleep apnea and quality of sleep compare to surgical treatment. The study performed an obstructive sleep apnea evaluation (polysomnography, endoscopy, degree of tonsillar hypertrophy, sleep apnea-related questionnaires and radiation inspection) with patients visiting sleep centers or otorhinolaryngology of three medical institutions due to sleep apnea. A total of 62 hospitalized patients with a chief complaint of snoring or sleep apnea were recruited. The 3 participants could not complete the study and dropped out; the 59 participants completed the study as planned. In the primary analysis of efficacy evaluation, the difference between the findings at baseline and visit 5 and the analysis for each medical institution were analyzed for AHI, PSQI, ESS and SaO2 . The mean AHI, indicating level of sleep apnea, at week 5 after treatment decreased. For PSQI for measuring the sleep quality, the measured value at visit 5 after treatment was increase. For ESS for measuring daytime sleepiness, the value also decreased. SaO2 during sleep also increased and all of these results were statistically significant. In the secondary analysis of comparison of success rate there was no statistical difference between the success rate of airway dilation using MAD and the success rate of UPPP. The difference in the success rates among the medical institutions was also not statistically significant. These findings indicate that this product has the comparative advantage to the surgery in terms of less complications and the low cost. ER -