TY  - JOUR
T1  - Biomimetic Apatite Deposition in Modified Dulbecco’s Phosphate-Buffered
Saline Solution on the Alkali-Heat Treated TI6AL4V
AU - Hamzah, Fazlena AU - Hazwani Hanib, Nurul AU - Omar, Zarina AU - Subuki, Istikamah 
JO  - Journal of Engineering and Applied Sciences
VL  - 14
IS  - 9
SP  - 3083
EP  - 3093
PY  - 2019
DA  - 2001/08/19
SN  - 1816-949x
DO  - jeasci.2019.3083.3093
UR  - https://makhillpublications.co/view-article.php?doi=jeasci.2019.3083.3093
KW  - Ti6Al4V
KW  -alkali treatment
KW  -heat treatment
KW  -biomimetic
KW  -Dulbecco’s Phosphate Buffered Saline
(DPBS)
KW  -medical implant
AB  - Simulated Body Fluid (SBF) solution has been used in biomimetic apatite coating. In some cases, the
apatite formation on the metallic surface may take up to 4 weeks in SBF solution. Increasing the concentration
of SBF seems to work in shortening the period of apatite formation yet the high concentration of unstable SBF
solution is not easy to handle. Another potential solution that mimics human blood plasma to hasten the apatite
formation is Dulbecco’s Phosphate Buffered Saline. The aim of this research was to investigate the formation
of apatite in Dulbecco&#146;s Phosphate Buffered Saline (DPBS) solution modified with CaCl<sub>2</sub> and MgCl<sub>2</sub> on the surface of alkali treated Ti6Al4V. The bioactive surface on Ti6Al4V was prepared by alkali etching using 5M
NaOH and 5M KOH and consolidated by heat treatment at 500 and 600&deg;C The morphology structure, phase
changes, wettability and chemical composition of apatite coating were characterised. The results demonstrated
that apatite coating in globular rosette-like shape was formed on the surface treated with NaOH and
subsequently heat-treated at 500&deg;C within 3 days of immersion time in DPBS solution. Significantly, the DPBS
solution can be used as a substitute in biomimetic solution for apatite coating at low processing temperatures
for bioactive coating of the medical implant.
ER  -