TY - JOUR T1 - The New Approach of Complex Control Law on Immunological System AU - Yermekbayeva, Janar J. AU - Myrzakul, Tolkynay JO - The Social Sciences VL - 10 IS - 6 SP - 1177 EP - 1182 PY - 2015 DA - 2001/08/19 SN - 1818-5800 DO - sscience.2015.1177.1182 UR - https://makhillpublications.co/view-article.php?doi=sscience.2015.1177.1182 KW - Control theory KW -theory of catastrophe KW -structurally-steady mapping KW -lyapunov function KW -mathematical modeling KW -immune system KW -HIFU therapy AB - In this study, we investigate a new mathematical models and approach of the control of tumors in organism. We consider the Immunological Model for the population dynamics of cells with control-factors representing the influence on the disease. We analysed the impact of the “D-factor” on the steady states and their stability and determine a control value. In these models, we studied the “D-factor” in “Umbilical” from catastrophe theory to impose control on tumor growth. By adjusting parameters, the models shows stationary states at which the immune system is stabilized and the number of tumor cells is either driven to zero or remains constant. Numerical simulations are carried out to confirm the theoretical findings to investigate the impact of the control parameters on the dynamic of the disease. The offered results can be used at theoretical studies for stabilization immune system at predicted level. These results are particularly relevant as new method in mathematical modeling and their applied views and for the prevention and early diagnostics of cancer and health improvement. ER -