O.A.  Suvorov, A.I.  Panait, V.M.  Bakhir, A.G.  Pogorelov, M.A.  Pogorelova, G.R.  Ivanisky, 
    Indirect Response of Early Mouse Embryo to Oxidative Stress Evoked in Apoptosis Model,
    Journal of Engineering and Applied Sciences,
    Volume 13,Issue 12,
    2018,
    Pages 4300-4304,
    ISSN 1816-949x,
    jeasci.2018.4300.4304,
    (https://makhillpublications.co/view-article.php?doi=jeasci.2018.4300.4304)
    Abstract: Quantitative laser microtomography was employed to measure the single cell volume. NMRI mouse
zygotes and 2-cell embryos were shown to exhibit the shrinkage at apoptosis induced with ROS (40 min., H<sub>2</sub> O<sub>2</sub> , 
0.2 mM). Unlike early embryos, there was no influence of<i> in vitro</i> apoptotic circumstances on mature oocytes,
direct precursor of early embryogenesis. Dulbecco&#146;s solution prepared from electrochemically reduced
bi-distilled water allows the low redox potential in both normal and apoptotic conditions. The data obtained
permit us to suggest that ROS sub-milimolar concentrations likely act as the signaling impact. Cys-loo receptors
containing thiol group may be considered as the target of hydrogen peroxide molecules.
    Keywords: Oocyte and early embryo;NMRI mouse;apoptosis;hydrogen peroxide;electrochemically reduced;quantitative laser microtomography;cellular volume;Oocyte and early embryo;NMRI mouse;apoptosis;hydrogen peroxide;electrochemically reduced;quantitative laser microtomography;cellular volume