Fouad A. Majeed, Khalid H.H. Al Ateah, Malik S. Mehemed, The Effect of Breakup Channel on the Fusion Reactions of Some Light and Medium Nuclei, Journal of Engineering and Applied Sciences, Volume 13,Issue 18, 2018, Pages 7511-7519, ISSN 1816-949x, jeasci.2018.7511.7519, (https://makhillpublications.co/view-article.php?doi=jeasci.2018.7511.7519) Abstract: The effect of coupled-channel calculations on the total fusion cross section σfus, the fusion barrier distribution Dfus and the reaction probability (prob.) for the light systems (6He+209Bi, 7Li+59Co) and the medium system (46Ti+64Ni). By means of a semiclassical and full quantum mechanical approaches are discussed. The semiclassical approach used in the present research based on the method of the Alder and Winther for Coulomb excitation. The results obtained from our semiclassical and full quantum mechanical calculations are compared with the available experimental data. The semiclassical calculations agrees reasonably with the full quantum mechanical treatment and they were able to reproduce the experimental data in details for the total fusion reaction cross section σfus the fusion barrier distribution Dfus and the probability of the reaction. Keywords: Breakup channel;fusion reactions;fusion barrier distribution;semiclassical;experimental data;mechanical calculations