S. Hadi Suryo, M. Haris Setiawan, J. Jamari, A. P. Bayuseno, For Children with Autism: Designing, Manufacturing and Testing the Universal Therapeutic Mattress, Journal of Engineering and Applied Sciences, Volume 14,Issue 11, 2019, Pages 3538-3548, ISSN 1816-949x, jeasci.2019.3538.3548, (https://makhillpublications.co/view-article.php?doi=jeasci.2019.3538.3548) Abstract: Every parent expects the birth of a child. The expected child of every parent is a perfect child with no flaws. Everyone does not want to be born in this world with disorder or disability. No parents are expecting the birth of a child with disability. The birth of a child with special needs does not exclude the rich, educated, poor, religious or non-religious families. Parents cannot resist the birth of a child with special needs. This research aimed to create a prototype in the form of universal therapeutic mattress for children with autism in Indonesia which aimed to provide comfort effects on the user by putting pressure on the body. There were 4 design concepts which were then designed using Fusion 360 for the selected design concepts. This therapy tool is used for children aged 8-15 years with height around 100-150 cm. The main material used was foam and cotton cloth for the convenience of the user. Then, a design concept was chosen that could reduce the stress index report by 3.8 or 1.28%. Keywords: Autism;therapy tool;Fusion 360;stress index;article history;received;accepted