F.C. Iheukwumere  , A.H. Abu  , F.C. Ndubisi  , 
    Effectiveness of Administration of Different Dose Rates of FSH + LH (Pergonal<SUP>&reg;</SUP>) on Superovulation, Hormonal Profiles and Leucocyte Status of Nigerian Red Sokoto (Maradi) Goats,
    Research Journal of Animal Sciences,
    Volume 2,Issue 4,
    2008,
    Pages 103-108,
    ISSN 1993-5269,
    rjnasci.2008.103.108,
    (https://makhillpublications.co/view-article.php?doi=rjnasci.2008.103.108)
    Abstract: Sixteen healthy, parous, Red Sokoto (Maradi) goats aged 2-4 years were used to study the effects of varying doses of FSH + LH (Pergonal<SUP>&reg;</SUP>) on superovulation, hormonal profiles and leucocyte status. The does were randomly assigned to 4 treatment groups consisting of 19.0 IU, 38.0 IU and 76.0 IU FSH + LH (Pergonal<SUP>&reg;</SUP>) and 1.0 mL physiological saline as the control treatment. The treatments were administered intramuscularly for 3 days. The results on the number of corpora lutea on the ovary did not show any significant differences (p&gt;0.05) between goats on 19.0 IU (5.36±0.46), 38.0 IU (6.15±1.14) and 76.0 IU (6.60±1.84) FSH + LH. The ovary did not show any significant differences (p&gt;0.05) between goats on 19.0 IU (5.36±0.46), 38.0 IU (6.15±1.14) and 76.0 IU FSH + LH (6.60±1.84). However, they differed significantly (p&lt;0.05) from goats on the control in the number of corporalutea on the ovary. The number of embryos recovered was not significantly different (p&gt; 0.05) between goats on 19.0 IU (4.35±0.82) 38.0 IU (4.50±0.65) and 76.0 IU FSH + LH (4.85±1.38), however, they differed significantly (p&lt;0.05) from goats on the control treatment (2.05±0.02). Goats treated on 19.0 IU FSH + LH (63.4±1.35%), 38.0 IU FSH + LH (67.8±1.25%) and 76.0 IU FSH + LH (75.6±2.51%) were similar (p&gt;0.05), but, they differed significantly (p&lt;0.05) from the control treatment (35.0±0.65%) in embryo recovery rate. There were significant differences (p&lt;0.05) between treatment groups in ova/embryo wastage. LH and FSH values were highest at 38.0 IU FSH + LH with (3.80±0.4) and (3.33±0.14) (iu L <SUP>1</SUP>), respectively. Progesterone and oestradiol showed higher values on 38.0 IU FSH + LH (51.91±0.36) and 19.0 IU FSH + LH (11.6±0.7) nmol L <SUP>1</SUP>, respectively. Higher neutrophil counts were observed in goats treated with 76.0 IU FSH + LH (75.64±1.48) nmol L <SUP>1</SUP>. The lymphocyte counts showed significant differences (p&lt;0.05) between the treatment groups.
    Keywords: Goats;superovulation;hormones;leucocyte