Mohammed Ali Alshehri,
Cytogenetic Effects of Methidathion Pesticide on Rat Bone Marrow Cells,
Environmental Research Journal,
Volume 8,Issue 2,
2014,
Pages 48-54,
ISSN 1994-5396,
erj.2014.48.54,
(https://makhillpublications.co/view-article.php?doi=erj.2014.48.54)
Abstract: Methidathion is a non-systemic organophosphorus insecticide.
Genotoxicity potential of methidathion was evaluated in rat bone marrow cells
(in vivo) using different doses based on LD50 by means of
micronucleus test. MNNCE (Micronucleated Normocromatic Erythrocytes) and MNPCE
(Micronucleated Polychromatic Erythrocytes), NDI (Nuclear Division Index) and
NDCI (Nuclear Division Cytotoxicity Index), necrotic and apoptotic cells were
recorded in rats bone marrow samples.
Keywords: Methidathion;micronucleus;NDI;toxicity;clastogenic effect