@article{MAKHILLJAVA201413154410,
title = {Phylogenetic Analysis of Viral Hemorrhagic Septicemia Virus (VHSV) Isolated from Olive Flounders (Paralichthys olivaceus)},
journal = {Journal of Animal and Veterinary Advances},
volume = {13},
number = {15},
pages = {952-957},
year = {2014},
issn = {1680-5593},
doi = {javaa.2014.952.957},
url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2014.952.957},
author = {Bo Kyu,Myung Han,Jong Man,Hyoung Joon,Bong Jo,Sang Yoon and},
keywords = {Korea,pathogens,glycoprotein,nucleotide,VHSV},
abstract = {Viral Hemorrhagic Septicemia Virus (VHSV) is the most important
viral pathogens that infects the olive flounders reared in Korean aquaculture.
Thirty VHSV isolates were identified in farmed olive flounders from 2007 to
2011 by using the Epithelioma Papulosum Cyprini (EPC) cell line. The genetic
diversity of the VHSV was evaluated by analyzing the nucleotide sequences of
the partial Glycoprotein (G) and Nucleocapsid protein (N) genes
of the 30 isolates. Researchers found that all the isolates were closely related
to the Japanese and North American genotype IVa which is clearly distinct from
the 3 European genotypes. The isolates formed a unique subgroup which was genetically
separated from the Japanese and North American isolates. The nucleotide sequences
of the 30 isolates exhibited very close identity with each other (>98.6%
identity). This study shows that the VHSV genotype IVa strains are widely distributed
throughout olive flounder farms in Korea.}
}