Zhuoying Zhang, Jinyang Lin,
The Influence of Polysaccharides from the Roots of Achyranthes bidentata on Biochemical Parameters Related to Oxidative Stress Induced by Exhaustive Exercise of Rats,
Journal of Animal and Veterinary Advances,
Volume 11,Issue 24,
2012,
Pages 4693-4696,
ISSN 1680-5593,
javaa.2012.4693.4696,
(https://makhillpublications.co/view-article.php?doi=javaa.2012.4693.4696)
Abstract: The main purpose of this study was to investigate the effects
of polysaccharides from the roots of Achyranthes bidentata (ABP) on exhaustive
exercise-induced oxidative stress by measuring related biochemical parameters
of rats. The animals were randomly divided into four groups (n = 10 in each
group): one control group and three ABP administered groups. The control group
was given saline solution and the administered groups were given different doses
of ABP (50, 100, 200 mg kg-1) by gavage once a day. After 21 days,
the rats performed an exhaustive exercise test on a graded treadmill, along
with the determination of related oxidative stress parameters. The results showed
that ABP could significantly increase Superoxide Dismutase (SOD), Glutathione
Peroxidase (GSH-Px) and Catalase (CAT) activities, decrease Malondialdehyde
(MDA) contents in muscle of rats which meant that ABP effectively attenuates
oxidative stress induced by exhaustive exercise.
Keywords: exhaustive exercise;biochemical parameters;oxidative stress;Achyranthes bidentata;Polysaccharides;rats