Manmohan  Singhal, Arindam  Paul, 
    Evaluation of Anti-Fungal Activity of Synthesized Chalcone Semicarbazone Derivatives,
    Research Journal of Biological Sciences,
    Volume 6,Issue 12,
    2011,
    Pages 632-634,
    ISSN 1815-8846,
    rjbsci.2011.632.634,
    (https://makhillpublications.co/view-article.php?doi=rjbsci.2011.632.634)
    Abstract: In the present study, researchers designed a Pharmacophore Model chalconesemicarbazone which is having hydrogen acceptor site, hydrogen donor site, lipophilic site, etc., using Ligandscout-2.02 software. A series of chalcone semicarbazones was synthesized and evaluated for their anti-fungal activity by Paper Disk Diffusion Method. Based on the results of an anti-fungal study, compound CS-10 was the most active compound. It was observed that methoxy substitution in aldehydic moiety and hydroxyl substitution in the acetophenic moiety significantly increased anti-microbial spectrum against fungi.
    Keywords: Anti-fungal;semicarbazones;chalcone;disk diffusion;lipophilic site;India