T.K. Nyengidiki, G. Basssey, C.F. Mmom, Limb Loss Following Deep Venous Thrombosis Associated with Huge Uterine Fibroid: Case Presentation and Review of Literature, International Journal of Tropical Medicine, Volume 15,Issue 3, 2020, Pages 44-46, ISSN 1816-3319, ijtmed.2020.44.46, (https://makhillpublications.co/view-article.php?doi=ijtmed.2020.44.46) Abstract: Uterine fibroids are common amongst nulliparous women in our environment. Vascular occlusion resulting in deep venous thrombosis as a complication is however, rare. A review of the medical record of a 40 years old nullipara, known hypertensive diabetic who presented with left lower limb gangrene due to left iliac vein thrombosis secondary to extrinsic compression by a uterine fibroid was carried out. She had a total abdominal hysterectomy and an above knee amputation of the left lower limb. Considering the high prevalence of uterine fibroids in our environment, it is pertinent for physicians to have a high index of suspicion when a woman presents with hip or left calf pain and a pelvic mass. This will ensure early intervention and prevent avoidable morbidities. Keywords: Complication;environment;amputation;hypertensive;avoidable morbidities