Wafaa A. Abd  El-Ghany, M.  Ismail, 
    Tackling of Experimental Colisepticaemia in Broiler Chickens Using Phytobiotic Essential Oils and Antibiotic Alone or in Combination,
    Research Journal of Poultry Sciences,
    Volume 6,Issue 3,
    2013,
    Pages 59-67,
    ISSN 1993-5285,
    rjpscience.2013.59.67,
    (https://makhillpublications.co/view-article.php?doi=rjpscience.2013.59.67)
    Abstract: This study was designed to compare between the efficacy of 
  a phytobiotic containing a mixture of essential oils of <I>Oreganum aetheroleum</I> 
  and an antibiotic containing ciprofloxacin as an active principle for the treatment 
  of experimental (<I>E. coli</I>) infection in broiler chickens. Two hundred, 
  day old broiler chickens were divided into 5 equal groups. The 1st group was 
  neither challenged nor treated but groups 2, 3, 4 and 5 were challenged with 
  <I>E. coli</I>. The 2nd group was challenged only while the 3rd, 4th and 5th 
  group were treated with phytobiotic, ciprofloxacin and phytobiotic and ciprofloxacin 
  combination, respectively. Results confirmed significant (p&lt;0.05) improvement 
  of productive performance parameters, reduction in signs, mortalities, post 
  mortem lesions and bacterial re-isolation, significant (p&lt;0.05) enhancement 
  in cell mediated and humoral immune responses, significant (p&lt;0.05) reduction 
  in levels of liver and kidney function tests as well as significant (p&lt;0.05) 
  increase in the total protein and globulin levels in chickens challenged with 
  <I>E. coli</I> and treated with either essential oils or ciprofloxacin compared 
  with challenged non treated chickens. Moreover, the best significant (p&lt;0.05) 
  results in all measured parameters were detected in group treated with combination 
  in comparison with those treated with single treatment. In conclusion, a mixture 
  of essential oils of <I>Oreganum aetheroleum</I> is effective for the treatment 
  of <I>E. coli</I> infection in broiler chickens when compared with ciprofloxacin. 
  However, combined treatment could be superior in controlling such infection 
  of broiler chickens.
    Keywords: Poultry;colibacillosis;phytobiotics;ciprofloxacin;treatment;phytobiotic