Research Journal of Pharmacology
ISSN: Online 1993-6019ISSN: Print 1815-9362
Abstract
To evaluate the efficacy and safety of intra‐gestational sac injection of Methotrexate in the management of Caesarean scar ectopic pregnancy (CSEP). This prospective study included 12 patients diagnosed with CSEP. Patients were administered Tab. Mefigest 200 mg orally on day D1 followed by intra‐gestational sac injection of Methotrexate (50 mg/m² body surface area) on D2 under anesthesia with ultrasound guidance. Serial serum ß‐HCG levels were monitored on D4, D7, D21, and D42 until levels decreased below 5 mu/ml. Follow‐up scans were conducted at 6‐8 weeks. All patients showed a significant decrease in ß‐HCG levels by D21, confirming the resolution of ectopic pregnancy without the need for surgical intervention. No major complications were reported and follow‐up scans showed no residual ectopic tissue. Intra‐gestational sac injection of Methotrexate is an effective and safe alternative to surgical management for patients with CSEP, offering a fertility‐preserving option.
How to cite this article:
Vaishali Khadke, Gauri Dank, Sandhya Bhattad and Rucha Dhokte. Caesarean Scar Ectopic Pregnancy: Hit the Target by Intra‐Gestational Sac Inj. Methotrexate.
DOI: https://doi.org/10.36478/10.36478/makrjp.2024.2.16.20
URL: https://www.makhillpublications.co/view-article/1815-9362/10.36478/makrjp.2024.2.16.20