First trimester vaginal bleeding is a common obstetric complication associated with increased risks of adverse pregnancy outcomes. This study evaluates the impact of first trimester vaginal bleeding on pregnancy outcomes within a tertiary care setting, aiming to provide insights into the potential implications for clinical management and patient care. This retrospective cohort study involved 200 women who presented with first trimester vaginal bleeding at a tertiary care hospital. Data on pregnancy outcomes were collected and analyzed, comparing women with and without first trimester bleeding. Statistical analyses included odds ratios (ORs), 95% confidence intervals (CIs) and p‐values to assess the relationship between first trimester bleeding and subsequent pregnancy outcomes. The study found that first trimester vaginal bleeding significantly increased the risk of miscarriage (OR 2.2, 95% CI 1.0‐4.8, p=0.04), preterm birth (OR 3.3, 95% CI 1.2‐9.1, p=0.02) and low birth weight (OR 2.5, 95% CI 1.1‐5.7, p=0.03). Although increases in risks for gestational hypertension and stillbirth were observed, these were not statistically significant (gestational hypertension: OR 2.7, 95% CI 0.8‐9.0, p=0.10., stillbirth: OR 2.6, 95% CI 0.5‐13.5, p=0.24). Management strategies such as progesterone supplementation were notably effective in improving outcomes among affected women. First trimester vaginal bleeding is associated with significant adverse impacts on several critical pregnancy outcomes. Early detection and appropriate management strategies are crucial in minimizing the negative effects associated with this condition. The findings underscore the importance of careful monitoring and tailored interventions for pregnant women presenting with early bleeding.
Pratima Mahabale, Preshit Chate and Ganesh Tondge. Impact of First Trimester Vaginal Bleeding on Pregnancy Outcomes in A Tertiary Care Setting.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.11.479.484
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.11.479.484