Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Spectrum of clinical manifestations of HIV infection varies in infants and children in different areas of the world. Present study was aimed to study clinical profile of HIV infection in paediatric age group at a tertiary care hospital. Present study was single‐center, prospective, observational study, conducted in children between 18 months 14 years of age confirmed to have HIV infection by ELISA/DOT assay according to WHO strategy II and/or III OR xhildren between 0 to 18 months born to seropositive mothers. Total 120 HIV seropositive pediatric patients attending ART OPD and IPD were studied. Maximum children were between 18 months 4 years (45%) were boys (58.3%)delivered vaginally (70.8 %) had vertical Mode of Transmission (97.5 %) and were completely immunized for age (64.2%). Mean age of presentation was 4.67±1.95 years. 118 (98.3%) mothers and 116 (96.7%) fathers were found to be reactive. According to WHO classification system for clinical staging of HIV disease, majority 45 children presented with clinical stage IV (37.5%) followed by stage III (25%) stage I (20.8%) and stage II (16.7%) at time of registration. Majority children had no evidence of immunosuppression (33.3%) followed by children with mild immunosuppression (22.5%) children’s with advanced immunosuppression (23.4%) and children with severe immunosuppression (20.8%). Tuberculosis was the most common opportunistic infection followed by chronic diarrhea. Conclusion: Most common symptom was failure to thrive followed by prolonged fever. Majority of children were in WHO clinical Stage 3 and 4. Tuberculosis was most common opportunistic infection.
How to cite this article:
K. Balkishan Choudhari, Shubhangi Patil Ganvir and Harish Tambekar. Study of Clinical Profile of HIV Infection in Paediatric Age Group at a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.4.115.121
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.4.115.121