Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Oral squamous cell carcinoma (OSCC) is a prevalent form of cancer associated with tobacco consumption. Histopathological grading provides insights into the aggressiveness and prognosis of OSCC. This study aims to explore the correlation between the histopathological grades of OSCC and the history and extent of tobacco consumption in patients. A cross‐sectional study was conducted with 200 participants diagnosed with OSCC. Histopathological grades were determined using standard criteria and were correlated with detailed tobacco consumption history, including duration, frequency and type. Statistical analyses were conducted to assess the relationship between the grades of OSCC and tobacco use patterns. The study found a statistically significant correlation between higher histopathological grades of OSCC and increased levels of tobacco consumption. A noticeable pattern of more severe carcinoma grades was evident among heavy and long‐term tobacco users. The results also highlighted specific histopathological characteristics that were more prevalent in association with certain types and patterns of tobacco use. The findings suggest a strong link between tobacco consumption and the severity of histopathological grades of OSCC. These results underscore the critical need for targeted tobacco cessation programs and early screening for OSCC, especially among populations with high tobacco use. Further research is recommended to explore the mechanisms underlying the relationship between tobacco‐induced carcinogenesis and OSCC progression.
How to cite this article:
Aiman Mahmood, Hafeza syeda farha Sultana and Idrees Akhter Afroze. Correlation between Histopathological Grades of Oral Squamous Cell Carcinoma and Tobacco
Consumption A Cross Sectional Assessme.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.4.147.151
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.4.147.151