Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
The gastrointestinal stromal tumors (GISTs) are neoplasms of mesenchymal origin, they represent 0.3% of neoplasm in the digestive tube. They are defined by the expression of CD117, a tyrosine kinase receptor of the growth factor. Aim of this study is to know the clinical, pathological immunohistochemical characteristics of patients who attend the hospital of ACSR Government Medical College, Nellore during June 2021‐May 2023. Fourty nine cases of GIST were found, in all cases, clinical data and the macroscopic aspect were studied microscopy and immunohistochemical characteristics were also checked. These cases are more frequent in women, in a proportion of 1.4:1, with an average age of 52‐year‐old. The treatment was full surgery, in 4 of them, a lymphadenectomy was done metastasis was found in one case. The average size of the tumors was 8 cm. The predominant histological pattern was fusocellular (81.5%), followed by epithelioid patterns (7.4%) and mixed (11.1%). The main locations were the stomach (48.1%), small intestine (40.7%), rectum (5.6%), omentum (3.7%) mesentery (1.9%). The malignant potential according to Fletcher's criteria were very low malignant potential (20.5%), low malignant potential (25%), intermediate potential (20.5%) high malignant potential (34.1%). All cases were positive for CD117.
How to cite this article:
Kande Srinivasulu, Swarupa Rani Ragi, Shaik Raja Husne Kalam, Sucharitha Pathivada and B.V. Sai Prasad. A Study of Gastrointestinal Stromal Tumors in a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.4.394.400
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.4.394.400