Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
To evaluate the effects of intravenous immunoglobulin (IVIG) treatment on motor nerve conduction in patients diagnosed with Guillain Barré Syndrome (GBS). This observational study, adhering to STROBE guidelines, involved fifty GBS patients from a rural medical college in central India. Nerve conduction studies (NCS) were performed on the median, ulnar, tibial and peroneal nerves at baseline and one week post‐IVIG treatment. The parameters assessed included distal motor latency, amplitude and conduction velocity. The study included 50 patients with clinically diagnosed GBS. Significant improvements in motor nerve function were observed post‐IVIG treatment, particularly in the amplitude of right median and ulnar nerves, and both amplitude and distal motor latency in the right peroneal and bilateral tibial nerves. The study recorded statistically significant differences in these parameters, suggesting an effective reversal in conduction deficits. IVIG treatment within the first week of GBS symptom onset is crucial and can significantly improve motor nerve function, as evidenced by NCS parameters. This study underscores the importance of timely diagnosis and initiation of therapy to enhance prognosis in GBS patients.
How to cite this article:
Vinod Shende, Sachin Pawar and A. Prashanth. Study of Motor Nerve Conduction in Pre and Post‐Immunoglobulin Treatment of Guillain Barré Syndrome.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.1.5
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.1.5