Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Regional anesthesia is preferred as it keeps patients awake, maintains airway reflexes, provides cardiovascular stability but has a discomfort of puncture site pain and recollection of surgery. Recently, there has been interest in inclusion of Intravenous Clonidine and Dexmedetomidine as adjuvants, to overcome patient’s discomfort. To compare the effects of intravenous Dexmedetomidine or Clonidine as adjuvants during bupivacaine spinal anaesthesia. A prospective, randomized trial was carried on 80 patients scheduled for elective surgeries under spinal anesthesia, forty in each group. Group A received 1 μg/kg of Dexmedetomidine with an infusion rate of 0.5 μg/kg/h, whereas Group B received 1 μg/kg of Clonidine with an infusion rate of 1 μg/kg/h. Maintenance infusion was administered after Subarachnoid block, following a loading dose that lasted for ten minutes. Patients were tested for time required to reach target sedation, analgesia, sensory and motor blockade. Additionally, the visual analogue score, side effects and hemodynamic parameters were noted and analyzed. Dexmedetomidine has significantly high sedation score, increased duration of sensory block‐412.88±10.19mins, motor block‐358.61±9.11mins, extended postoperative analgesia ‐488.05±12.27mins compared to Clonidine 283.51±11.42mins, 217.32±8.56mins and 372.67±13.22mins respectively. When compared, the groups receiving Clonidine and Dexmedetomidine, it was observed that the VAS scores of the former group were much lower. Premeditation with intravenous Dexmedetomidine was superior to intravenous Clonidine in terms of providing early sensory and motor block, extended postoperative analgesia and adequate sedation.
How to cite this article:
D. Preethi Fatima, Sneha Susan Koshy, Saranya and C.M. Ragashree. Comparison Between Intravenous Dexmedetomidine and Clonidine as Adjuvants to Bupivacaine Spinal Anaesthesia.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.154.159
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.154.159