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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Prospective Comparative Study of Crystalloid Coloading Versus Preloading for Prevention of Spinal Anaesthesia Induced Hypotension in Elective Caesarean Section

C.M. Ragashree, G. Beula, Sneha Susan Koshy and G.L.K. Harish
Page: 167-171 | Received 19 Apr 2024, Published online: 11 Jun 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.7.167.171

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Abstract

Cesarean section is preferably performed under spinal anesthesia owing to its quick onset, dense neural block, minimal fetal drug transfer and toxicity. However sympathetic inhibition causes hypotension, treated by intravenous fluid boluses. Brief duration of crystalloid infusion in the intra vascular compartment raises timing concerns regarding rapid fluid redistribution and excretion, reducing preload’s efficiency in preventing hypotension. Co‐loading is favored as it increases the intra vascular volume during the vasodilatory phase of sympathetic inhibition. To compare the effectiveness of crystalloid preloading and co‐loading against the incidence of hypotension after spinal anaesthesia in caesarean section. A prospective comparative study was conducted in 60 parturient. Patients were randomly assigned to either groups by consecutive sampling. Before spinal anesthesia, parturients in group P received a preload of 15 ml/kg ringer's lactate over 20mins. Parturient in group C received 15ml/kg ringer's lactate over 20mins, immediately following spinal anesthesia. Heart rate, systolic, diastolic blood pressure, mean arterial pressure, incidence of hypotension and ephedrine use were evaluated. Results were noted and analysed. Statistically significant difference was present in the incidence of spinal anesthesia induced hypotension between the preload and co‐load group. The two groups differed with heart rate, blood pressure, mean arterial pressure, nausea and vomiting. The group P also required more ephedrine than group C. Co‐loading crystalloid was more effective than preloading for preventing maternal hypotension following spinal anesthesia.

How to cite this article:

C.M. Ragashree, G. Beula, Sneha Susan Koshy and G.L.K. Harish. Prospective Comparative Study of Crystalloid Coloading Versus Preloading for Prevention of Spinal Anaesthesia Induced Hypotension in Elective Caesarean Section.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.167.171
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.167.171