Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Osteoporsis is a condition characterized by decreased bone strength and abnormal bone quality predisposing a person to an increased risk of fracture. The most common fractures seen in osteoporotic patients are vertebral compression fractures, followed by hip fractures. Zoledronic acid reduces the rate of bone resorption. This study evaluates the functional effect of zoledronic acid in vertebral osteoporosis. This is a prospective study done at Sree Mookambika Institute of Medical Sciences, Kulasekharam. Patients of both the sexes presenting with low back pain for more than 6 weeks duration were screened, 30 patients were selected for the study. VAS chart and Oswestry Disability Index questionnaire were given. 5 mg zoledronic acid infusion was administered over a minimum duration of 15 min under monitoring and observed for one day for adverse events and allergic reactions. A total of 30 patients were selected for the study. Major age group of patients with low back ache are between the age of 56‐60 years. 3s0 patients included in the study who were found to be osteporotic, among them, 20 were females and 10 were male patients. All the patients were followed at 3 months and 6 months At the end of 6 months ODI scores were 31.4. Comparison of T‐score of initial visit and after 6 months follow‐up after infusion of zoledronic acid showed excellent results. In patients with vertebral Osteoporosis, Zoledronic acid is considered as very effective and preferable bisphosphonates for the treatment and prevention.
How to cite this article:
S.L. Binesh, Zakir Hussain Mohamed, G. Rohin and M.D. Sheriff. Functional Outcome and Efficacy of Zoledronic Acid in Patients With Vertebral Osteoporosis: A Prospective Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.208.211
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.208.211