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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Efficacy of Intralesional MMR in Extensive and Recalcitrant Warts: An Open Uncontrolled Study

K. Vivekanandh, S. Shakthi Juwala, Anandan Govindaraj Vimal Kumar, R. Agnes Varshini, P.A. Sree Parvathi, J.A. Reshma, A.J.S. Pravin and J. Nivinsimon
Page: 218-220 | Received 02 May 2024, Published online: 13 Jun 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.7.218.220

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Abstract

Extensive warts is a challenging condition to treat. Intralesional MMR is a new modality which acts by enhancing cell‐mediated immunity against the warts. To evaluate the efficacy and safety of intralesional MMR in extensive and recalcitrant warts. Open uncontrolled study. 60 patients with multiple warts of varying sizes and duration were included in the study. 0.2‐to 0.5‐mL MMR solution was injected at the base of the wart. A maximum of 5 warts were injected per session at 3‐week intervals until resolution or for a maximum of 4 treatments. Patients were followed up for 6 months to detect any recurrence. Data were compiled in MS Excel and analyzed with the SPSS statistical software version 20. Complete response was seen in 41/60 (68.3%), partial response in 11/60 (18.3%) and no response in 8/60 (13.3%). Average sittings required to achieve complete resolution was 3.54. Side effects like erythema, oedema, pain and flu like symptoms were seen in 10% which were either self limiting or managed with analgesics. Recurrence was seen in 8%. Intralesional MMR is effective, safer and an inexpensive treatment option for extensive and recalcitrant warts.

How to cite this article:

K. Vivekanandh, S. Shakthi Juwala, Anandan Govindaraj Vimal Kumar, R. Agnes Varshini, P.A. Sree Parvathi, J.A. Reshma, A.J.S. Pravin and J. Nivinsimon. Efficacy of Intralesional MMR in Extensive and Recalcitrant Warts: An Open Uncontrolled Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.218.220
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.218.220