Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Globally, glaucoma is the most common cause of irreversible blindness. Primitive Open Angle Glaucoma (POAG) typically exhibits no symptoms until the illness reaches an advanced stage. One of the main risk factors for the development of POAG is intraocular pressure (IOP). However, some instances continue to proceed despite IOP management, supporting the hypothesis that the pathophysiology of glaucoma must involve additional independent risk factors. Contradictory results from recent epidemiological research have raised the possibility that hyperlipidemia and glaucoma are related. To determine the association between serum lipid levels and primary open‐angle glaucoma. The current study was a case‐control study with a total of 80 subjects, including 40 patients with POAG documented by an array of clinical tests and 40 age‐matched controls, conducted in the department of Ophthalmology, Sree Mookambika Institute of Medical Sciences. All patients underwent ophthalmic examinations. Total cholesterol, triglycerides (TG), low density lipoproteins (LDL) and high density lipoproteins (HDL) were measured as part of a fasting lipid profile. Using SPSS 24 software, statistical analysis was carried out using the chi square and unpaired t‐tests. A p‐value of less than 0.05 was considered significant. The mean age of the patients was 63.45±4.56 while that of the controls was 61.78±5.17 (p = 0.103). High total cholesterol levels (>200 mg/dl) were found in 20 (50%) cases and 8 (20%) controls. High serum triglyceride levels (>150 mg/dl) were found in 19 (47.5%) cases and 13 (32.5%) controls. High LDL levels (130 mg/dl) were found in 24 (60%) cases and 12 (30%) controls. Low HDL levels (<40 mg/dl) were found in 15 (37.5%) cases and 3 (7.5%) controls. As for the mean serum triglyceride levels, they were 158.66±38.34mg/dl and 139.38±21.57mg/dl, respectively, for the mean LDL levels, they were 139.98±27.88 mg/dl and 116.75±18.56 mg/dl and for the mean HDL levels, they were 36.71±10.05 mg/dl and 42.67±7.77mg/dl, respectively. The mean cholesterol, triglyceride and LDL levels were significantly higher in cases than in controls (p<0.05). A substantial correlation has been shown between dyslipidemia and a higher incidence of POAG. Hence, managing dyslipidemia may be a viable prophylactic measure for POAG.
How to cite this article:
R. Jeyanthi, S. Arsha Ressal, Rajeevan , Biju Gopal, Mathew tony and Rinita . Association Between Primary Open‐Angle Glaucoma and Serum Lipid Profile.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.221.225
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.221.225