Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Laryngoscopy and endotracheal intubation are often associated with hypertension as well as tachycardia as a result of temporary sympathoadrenal activation. Sudden hemodynamic response can have detrimental effects on patients suffering from cardiovascular and cerebrovascular illnesses, including arrhythmias, cardiac failure, elevated ICP and cerebral hemorrhage. Therefore, one of the essential steps in the effective induction of general anesthesia is to eliminate such responses. Due of this, a variety of adjuvants have been used, with differing degrees of success, including opioids, lignocaine, nitroglycerine, beta‐blockers and magnesium sulphate. To compare the hemodynamic changes to direct laryngoscopy and tracheal intubation between intravenous and nebulized forms of lignocaine. The present study was a prospective study conducted in 64 patients ASA Grade I and II patients between the ages of 20 and 60 of either gender scheduled for elective procedures under general anaesthesia were divided into two groups, Group A and Group B, with a sample size of 32 each. Patients in Group A received nebulization with 2% lignocaine 2 mg/kg for 10 minutes, while Group B received 2% lignocaine 2 mg/kg intravenously 90 seconds before induction. Heart rate (HR), blood pressure (BP) at both systolic and diastolic levels, mean arterial pressure (MAP) and basal values were measured, as well as at the 1, 3, 5, 7 and 10 minute following intubation. SPSS 20.0 was used for data analysis and the t test and Chi square were used to examine the relationship. The HR, SBP, DBP and MBP in the current study increased one minute after laryngoscopy and intubation, indicating a rise over the baseline value. In Group B, it was seen that the high hemodynamic values began to decrease by 10 minutes to the base line value. However, at 1,3 and 5 minutes, the HR, SBP, DBP and MBP in group A were significantly lower and statistically significant (p<0.05). Nebulized lignocaine performed somewhat better than intravenous lignocaine in terms of reducing the presser response to laryngoscopy and endotracheal intubation without causing severe adverse effects.
How to cite this article:
G.L.K. Harish, Devanand , C.M. Ragashree and D. Preethi Fatima. Comparison of Intravenous Versus Nebulised Lignocaine in Attenuation of Presser Response to Laryngoscope and Intubation.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.272.276
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.272.276