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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Study of Correlation of Apolipoprotein B and Dyslipidaemia in Type 2 Diabetes Mellitus and its Relation with Albuminuria in Tertiary Care Hospital

K.A. Ateeb Ahmed, G. Narasimha Shastry, B. Devadas Rai, Mohammed Bilal Hussain, Y. Praneeth Charan Reddy, Hanumanthakari Prudhvirajrana and Koot Snehal Rajkumar
Page: 400-404 | Received 20 Apr 2024, Published online: 22 Jun 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.7.400.404

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Abstract

The aim of the present study was to assess the correlation of Apo‐lipoprotein B and dyslipidemia in Type 2 Diabetes mellitus and its relation with Albuminuria. This Cross‐Sectional Study was conducted in the Department of General Medicine, Kanachur Institute of Medical Sciences, Mangalore, Karnataka in the year (June 2022‐June 2024) for 2 years with 100 patients. Mean age of the study population was found to be 52.48±12.96 years with minimum and maximum age being 22 and 75 respectively. Among 100 patients, 55 (55%) and 45 (45%) patients were accordingly female and male. It was observed that 52 (52%), 14 (14%), 6 (6%), 6 (6%), 3 (3%) 10 (10%) patients had HTN, IHD, CKD, CVA, Hypothyroidism and Other comorbidities correspondingly. Total of 9 (9%) patients had no comorbidities at all. Total of 20 (20%) and 80 (80%) patients belonged to HbA1c values <7 and >7 groups respectively. Distribution of ACR values with respect to different ranges of TC was not statistically significant (P>0.05). Distribution of ACR with respect to HDL levels was fond to be suggestively significant at 91% level of confidence. Different level of triglyceride (0‐10, 11‐200 and >200) distribution of ACR (404(52.095‐998.2), 713.6(81.5775‐1158.8) and 350(144.5‐770.5)) was not statistically significant. There was no significant difference was established in distribution of ACR with respect different levels of APO‐A1, APO‐B and APO B/APO A1. Significant positive correlation was found among TC, TG, LDL VLDL ApoB with correlation coefficient of 0.4, 0.34, 0.47, 0.24 and 0.32 respectively (P<0.05). In the present study, there was a significant positive correlation between Apolipoprotein B and albuminuria among patients with type 2 diabetes mellitus. There was also a positive correlation between Apolipoprotein B and dyslipidaemia among these patients, who showed elevated total cholesterol, LDL cholesterol triglyceride levels.

How to cite this article:

K.A. Ateeb Ahmed, G. Narasimha Shastry, B. Devadas Rai, Mohammed Bilal Hussain, Y. Praneeth Charan Reddy, Hanumanthakari Prudhvirajrana and Koot Snehal Rajkumar. A Study of Correlation of Apolipoprotein B and Dyslipidaemia in Type 2 Diabetes Mellitus and its Relation with Albuminuria in Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.400.404
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.400.404