files/journal/2022-09-03_18-51-40-000000_599.png

Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
About US
Editors
Issues
Pages
Indexed in
113
Views
13
Downloads

A Prospective Study to Evaluate Clinico-radiological and Histopathological Features ,Surgical Outcome in Patients with Spinal Tumors

Pavan Shetty, Vivek Kankane, Avdhesh Shukla, Gajendra Pal Uikey and Avinash Sharma
Page: 436-443 | Received 21 May 2024, Published online: 23 Jun 2024

Download Citation
https://doi.org/10.36478/10.36478/makrjms.2024.7.436.443

Full Text Reference XML File PDF File

Abstract

Spinal tumors are less common than skull tumors and can be primary, originating from the spinal cord, meninges, or bones, or metastatic, spreading from other body parts. Despite sharing histopathological similarities with intracranial tumors, primary spinal tumors are ten times less frequent. Symptoms are often vague, leading to misdiagnoses such as degenerative spinal disease or herniated discs. Magnetic resonance imaging (MRI) is the most reliable method for diagnosing spinal tumors, enabling precise differentiation of soft-tissue elements and guiding surgical intervention. This study aimed to Evaluate Clinico-Radiological And Histopathological Features ,Surgical Outcome In Patients With Spinal Tumors. This prospective study, conducted over two years (September 2022 to August 2024) at the Department of Neurosurgery, GRMC Gwalior, investigates spinal and spinal cord tumors in 50 patients confirmed through neuro-radiological features. Patients unwilling to participate or previously operated on for spinal tumors with recurrence are excluded. The study includes clinical assessments of neurological status, MRI of the suspected spine site, surgical management, patient functional outcomes using modified Nurick’s Grading and histopathological examination of tumor biopsies. The research focuses on patients admitted to the JAH Neurosurgery Department, Gwalior. The study analyzed 50 patients with spinal and spinal cord tumors, revealing key demographic and clinical characteristics. Participants were predominantly over 60 years old (50%), male (56%) and urban residents (52%). A significant portion was unemployed (60%), with varying education levels. Clinically, 98% had a history of back pain, 92% experienced lower limb weakness and 52% reported loss of bladder and bowel functions. Most underwent biopsy (64%) and received combined surgery and chemotherapy (84%). Histologically, adenocarcinoma of the prostate was the most common tumor (32%), followed by multiple myeloma (18%) and invasive ductal carcinoma of the breast (16%). Tumor distribution varied by age, originality (primary vs. secondary), nature (benign vs. malignant) and anatomical location, with extradural tumors being the most prevalent (88%). Adenocarcinoma of the prostate was frequently found in the lumbar region (43.47%). The data underscore the diversity in tumor types, patient demographics and clinical presentations in this cohort. The study highlights the importance of comprehensive clinical, ultrasonographic and histopathological evaluation in the diagnosis of ovarian lesions. The ORADS classification and color Doppler scoring systems provide valuable diagnostic accuracy and their combined use can significantly enhance the differentiation between benign and malignant ovarian lesions. Early and accurate diagnosis is crucial for effective management and improved patient outcomes.

How to cite this article:

Pavan Shetty, Vivek Kankane, Avdhesh Shukla, Gajendra Pal Uikey and Avinash Sharma. A Prospective Study to Evaluate Clinico-radiological and Histopathological Features ,Surgical Outcome in Patients with Spinal Tumors.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.436.443
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.436.443