Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
146
Views
11
Downloads
Abstract
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by joint pain, stiffness, swelling, impaired joint function, and elevated levels of acute‐phase reactants. Pain is a significant source of discomfort for RA patients. Vitamin D, known for its immunomodulatory effects, has shown potential efficacy in RA management, indicating its possible therapeutic benefits for these patients. This study aimed to assess the efficacy of vitamin D in mitigating the inflammatory response and subsequently alleviating pain in RA patients. The study involved 123 RA patients attending our tertiary care center. Participants were divided into two groups: one received vitamin D supplementation, while the other was given a placebo. Disease activity and Visual Analog Scale (VAS) scores were recorded at baseline and at 1‐month and 3‐month follow‐ups. At baseline, vitamin D levels were inversely correlated with disease activity. In the vitamin D group, the mean VAS score did not decrease significantly from baseline at 3‐month follow‐up. Similarly, in the placebo group, the mean VAS score did not decrease significantly from baseline at 3‐month follow‐up. Vitamin D supplementation did not result in a statistically significant improvement in VAS scores, indicating the need for further research to evaluate the role of vitamin D in RA treatment.
How to cite this article:
Shashank Tyagi, Ankit Agarwal, Mrinal Ranjan Srivastava and Nayan Silawat. Exploring the Link Between Vitamin D Deficiency and Pain in Rheumatoid Arthritis: A Correlative Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.7.605.609
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.7.605.609