Organophosphate (OP) poisoning is a significant global health issue, resulting in nearly 3 million cases and over 200,000 deaths annually. Understanding the factors influencing recovery outcomes is crucial for improving patient prognosis.This study aimed to evaluate the impact of early intervention and clinical variables on recovery outcomes in OP poisoning cases. A retrospective cohort study was conducted at a tertiary care center, analyzing medical records of patients aged 14 years and older with confirmed OP poisoning. Data were collected (June 2023‐May 2024 ) on demographics, clinical signs, time to presentation, treatments administered, duration of hospital stay, and patient outcomes. Statistical analyses included descriptive statistics, chi‐square tests, t‐tests, correlation and regression analyses. The study included 78 patients, with a mean age of 28.92 years (SD=12.81) and a balanced gender distribution (52.56% males, 47.44% females). Early intervention, including the time to hospital presentation and administration of first aid, did not significantly impact patient recovery (p>0.05). Clinical signs such as heart rate, pupil size, aspiration and crepitations showed weak correlations with patient outcomes. These findings suggest that demographic factors and early interventions alone are not strong predictors of recovery. Demographic factors such as age and gender, along with early interventions, do not significantly influence recovery outcomes in OP poisoning cases. The weak correlation between clinical signs and patient outcomes indicates that other factors may play a more critical role in determining prognosis. Further research is needed to identify additional predictors and improve comprehensive management strategies to enhance patient outcomes and reduce the public health burden of OP poisoning.
Dinesh Singh Mahor, Divyansh Gupta and Ritesh Yadav. Assessing the Impact of Early Intervention and Clinical Variables on Recovery in Organophosphate Poisoning Cases.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.145.149
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.145.149