Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Compare the Efficacy of Oral Clonidine and Oral Pregabalin Premedication 90 Min Prior to Surgery in Attenuating the Adverse Haemodynamic Responses to Laryngoscopy and Tracheal Intubation with Respect to Heart Rate
H. Prathibha and Sunil Kumar Mooknoor
Page: 251-256 | Received 28 May 2024, Published online: 15 Jul 2024
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Abstract
Laryngoscopy and tracheal intubation are the most essential tools of an anaesthesiologist in the airway management. To compare the efficacy of oral clonidine and oral pregabalin premedication 90 min prior to surgery in attenuating the adverse haemodynamic responses to laryngoscopy and tracheal intubation with respect to heart rate. 100 adult patients of ASA grade I and II in the age group of 18‐50 years of both sex were included in the study and were randomly divided into two groups of 50 each. Group A received oral tablet clonidine 0.3 mg 90 minutes before surgery while group B received oral tablet pragabalin 150 mg 90 minutes before surgery. Both groups were uniform in their distribution of age, weight, and sex. They had similar physical status with no coexisting disease. Both groups were managed with the same anaesthetic protocol. Haemodynamic variable like Heart Rate, was recorded pre‐induction, post‐induction, immediately after intubation and post‐laryngoscopy (1,3,5,10 minutes) vitals were noted. In oral clonidine group there was significant attenuation of heart rate in all time period. In oral pregabalin group there was no significant attenuation of haemodynamic response in heart Rate. Clonidine is better compared to pregabalin in attenuating adverse hemodynamic response to direct laryngoscopy and tracheal intubation with respect to heart rate.
How to cite this article:
H. Prathibha and Sunil Kumar Mooknoor. Compare the Efficacy of Oral Clonidine and Oral Pregabalin Premedication 90 Min Prior to Surgery in Attenuating the Adverse Haemodynamic Responses to Laryngoscopy and Tracheal Intubation with Respect to Heart Rate.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.251.256
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.251.256