Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
To assess the clinical profile of subclinical hypothyroidism in children of 1‐18 years of age at the time of presentation. The study was conducted among the children attending the paediatric and endocrinology departments of a tertiary care hospital at western India, (Gujarat). The statistical analysis was performed by IBM SPSS Statistics 20 version. Among the 40 children who were part of the study, the average age of presentation was 9.7 years. 45% of the children were males and 55% were females. The most common presenting symptoms were reduced physical activity (55%), weight gain (50%), constipation (50%), dry skin (50%) and poor scholastic performance (45%) and most common signs were pallor (55%) and delayed dentition (40%). Out of the 40 cases, 14 cases (35%) had a positive family history of thyroid disease in one of the parents and 1 case (2.5%) had family history of endocrine disease other than thyroid related disease running in the family. Among the anthropometric measures, 17.5% had short stature and 22% were overweight and 34% were obese. The normal range of TSH was taken as 0.5‐5.0 mIU/L and all cases had TSH level above 5.0 mIU/L. In this study the mean TSH level was 6.86±8.4 mIU/L. Furthermore, thyroid antibodies were done in 19 cases out of which 7(36.8%) were elevated. USG thyroid was done in just 2 cases which showed diffuse glandular enlargement and focal nodule, respectively in each of the cases. Subclinical hypothyroidism affects growth and development of children. It is associated with various clinical manifestations and risk factors. Thyroid function tests and thyroid antibodies should be done in children with suggestive symptoms and signs. Early diagnosis and treatment may prevent complications and improve outcomes.
How to cite this article:
Dimple Vishnubhai Patel, Harshkumar Bariya, Ashvin Ishvarbhai Dave and Chandan Narwani. Clinical Profile of Subclinical Hypothyroidism in Children Attending Tertiary Care Centre in Western India.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.324.327
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.324.327