Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Iron is an important mineral whose metabolism is tightly regulated in our body. Iron is capable of initiating oxidative stress when in excess. Type 2 Diabetes mellitus is achronic disorder of glucose metabolism with multiple causes. Ferritin is a protein that storesiron in the body. Iron can affect the metabolism of glucose by influencing insulin’s release and actions. We aimed at determining and comparing the serum levels of Iron, Total iron binding capacity(TIBC) and Ferritin in T2DM and healthy subjects and to correlate these with blood glucose levels. It was a case control study, which involved 50 T2DM patients and 50 controls. The study was undertaken in Subbaiah Institute of Medical Sciences. Serum blood glucose, Iron, TIBC were estimated in auto analyser and serum ferritin was es timated by chemil umin escence method. Statistical analysis: Mann Whitney Utestand Median, interquartil erange was applied. Spearman’srh ocorrelation was applied for correlations. p<0.05 was considered as statistically significant. Blood sugar levels and serum Ferritin levels were increased significantly in cases. Whereas serum iron and TIBC were not significantly elevated in cases. Only Ferritin showeda significant positive correlation with blood sugar levels. Increased levels of iron can lead to oxidative damage and lead to complications in diabetes mellitus patients. Hence frequent monitoring of serum iron and ferritin levels isadvisableinT2DM.
How to cite this article:
A. Jenish Babu, Thilagar , Prem Kumar and Yokesh . Effects of Iron on Blood Glucose Levels in Type 2 Diabetes Mellitus: A Study in Tertiary Care Centre.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.349.353
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.349.353