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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Study of the Association Between Post‐Stroke Depression and Lesion Type, Laterality and Location

Bhavika Mansharamani, Jitendra Keshwani, Rahul Jain, Srikanth Reddy, Himanshu Mansharamani, Hiral Kotadia, Apurva Tiwari and Ayushi Soni
Page: 390-396 | Received 04 May 2024, Published online: 30 Jul 2024

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https://doi.org/10.36478/10.36478/makrjms.2024.8.390.396

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Abstract

Stroke is one of the major causes of morbidity and mortality worldwide. Post‐stroke neuropsychiatric manifestations are commonly seen and are associated with poorer functional outcome and quality of life. Depression is one of the most prevalent post‐stroke neuropsychiatric manifestations, occurring in about 55% patients. Studies have shown that some neuroanatomical variables are more commonly associated with the occurrence of depression in the post‐stroke period. This study attempted to find the association between cerebrovascular lesion variables and depression. Forty four subjects with the history of first ever stroke, with duration after stroke being >2 weeks and <1 year, were interviewed using a semi‐structured proforma. Variables of stroke lesion type, laterality and location were collected using Magnetic Resonance Imaging (MRI). Depression was assessed using the DSM‐5 TR criteria for Major Depressive Disorder and severity of depression was measured using the Hamilton Depression Rating Scale (HDRS). Level of independence in the activities of daily living (ADLs) was assessed using the Barthel Index(BI). Post‐stroke depression was diagnosed in 27(61.4%) patients of stroke. Out of 44 patients of stroke, 76.9% patients with a left sided cerebrovascular lesion and 76% with a frontal lobe lesion were diagnosed with post‐stroke depression (PSD). PSD was found to be significantly higher in patients with a left hemispheric lesion and involvement of the frontal cortex. However, lesion size did not show any significant difference in Post‐stroke depression.

How to cite this article:

Bhavika Mansharamani, Jitendra Keshwani, Rahul Jain, Srikanth Reddy, Himanshu Mansharamani, Hiral Kotadia, Apurva Tiwari and Ayushi Soni. A Study of the Association Between Post‐Stroke Depression and Lesion Type, Laterality and Location.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.390.396
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.390.396