Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Attenuation of Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation: Comparison of Esmolol and Lignocaine for Elective Surgeries Under General Anaesthesia
Karthik V. Menon, M.B. Sudarshan and M. Reshma
Page: 514-517 | Received 20 Jun 2024, Published online: 31 Jul 2024
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Abstract
We compared the effects of intravenous esmololand lignocaine as premedicantin attenuation of hemodynamic response to laryngoscopy and intubation in normotensive patients undergoing elective surgery. A total of 60 patients undergoing general anesthesia were enrolled in the study and were randomly allocated into two groups of 30 each. Group 1 patients received intravenous esmolol 1mg/kg 3 minutes before intubation and Group 2 patients received intravenous lignocaine 1.5 mg/kg 3 minutes before intubation. Both groups were matched for age, sex, BMI and ASA grade. The highest HR recorded at the time of intubation was 90.2±12.4(3.2% above baseline) and 106.2±15.6(26.5% above baseline) in group1 and 2 respectively. This was statistically significant (p value‐0.010). With respect to SBP, DBP and MAP there was no statistically significant difference between the two groups. Intravenous esmolol 1mg/kg given 3 minutes before intubation was found to be more effective in controlling heart rate to laryngoscopy and intubation compared to intravenous lignocaine(1.5mg/kg) given 3 minutes before intubation and with respect to systolic, diastolic and mean arterial pressures both the drugs were comparable.
How to cite this article:
Karthik V. Menon, M.B. Sudarshan and M. Reshma. Attenuation of Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation: Comparison of Esmolol and Lignocaine for Elective Surgeries Under General Anaesthesia.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.514.517
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.514.517