Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Exploring the Dynamics of Plasmodium Falciparum Infection: Incidence, Clinical Presentations, Complications and Therapeutic Responses
Jatin Jitendra Bamania, Jugal Tarunkumar Chavda, Shaily Rakholiya, Sunil Tyagi and Paranshi Desai
Page: 576-580 | Received 01 Jul 2024, Published online: 11 Aug 2024
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Abstract
Falciparum malaria can progress rapidly, as a part of complications major organ system dysfunction such as cerebral malaria. The risk of death is 20% even with proper therapy. This rapid progression to complicated malaria is most common in those without immunity, such as children in the tropics or traveller from temperate zones. The present study was carried at the Medical Ward of the tertiary care hospital, to find out incidence of P falciparum malaria, with typical and atypical presentation, and therapeutic response. Clinical study of 50 adult cases of Plasmodium Falciparum malaria has been carried out at tertiary care hospital with prior approval. Data was collected for one year. All the cases of Plasmodium Falciparum positive on peripheral smear examination were included in this study. In a study on Plasmodium falciparum malaria: The highest incidence was in the 21‐30 age group (34%) followed by the 41‐50 age group (18%). Out of 50 patients, 72% were male and 28% were female. Complicated cases accounted for 54%, with a higher proportion in males (40%) compared to females (14%). Common symptoms included fever (100%), vomiting (56%), nausea (54%), body ache (46%) and headache (44%). Splenomegaly was present in 38% of cases, mostly mild (63.15%), while hepatomegaly was observed in 8%. Anemia was present in 36% of patients, with 22% having moderate anemia. Complications were seen in 54% of patients, with cerebral malaria (18%), convulsions (12%), hyperpyrexia (10%), hypoglycemia (10%) and pregnancy‐related complications (14%) being the most common. The study on Plasmodium falciparum malaria highlighted a higher incidence in the 21‐30 age group, with males being more affected than females. Complicated cases were prevalent, with common symptoms including fever, vomiting and nausea. Complications such as cerebral malaria, convulsions and hypoglycemia were observed in a significant portion of patients. Further attention to early diagnosis and management strategies for severe manifestations, especially in high‐risk age groups, is crucial for improving patient outcomes and reducing complications associated with Plasmodium falciparum malaria.
How to cite this article:
Jatin Jitendra Bamania, Jugal Tarunkumar Chavda, Shaily Rakholiya, Sunil Tyagi and Paranshi Desai. Exploring the Dynamics of Plasmodium Falciparum Infection: Incidence, Clinical Presentations, Complications and Therapeutic Responses.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.576.580
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.576.580