Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Comparative Study of Effects of Preloading or Co‐Loading with Crystalloids in Emergency LSCS on Fetal Acid Base Analysis in Normal Vs Preeclamptic Mothers
Neha Sharma, Rajdeep Kour, Neha Sharma, Santosh Devi, Jasmine Chowdhary and Isha Gupta
Page: 68-72 | Received 18 May 2024, Published online: 07 Jul 2024
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Abstract
Caesarian section is one of the most commonly performed surgical procedure worldwide and 80‐90% of them are performed under spinal anaesthesia. Maternal hypotension during spinal anaesthesia for caesarian section can lead to maternal complications (nausea, vomiting, giddiness) as well as fetal complications such as fetal hypoxia by impairing uteroplacental blood flow which can be detected by umbilical cord blood gas analysis. This study was conducted to compare the effectiveness of Preloading versus Co‐loading with crystalloids in prevention of spinal anaesthesia induced maternal hypotension and fetal acidosis in normal and pre‐eclamptic mothers during caesarian section and its role in preventing fetal hypoxia by monitoring umbilical cord blood gas analysis. 80 singleton full term pregnant patients (20‐35yrs of age) scheduled for emergency caesarian section were randomly divided into 4 groups, 20 each. Group A with normal pregnant females and Group C with Pre‐eclamptic females were Preloaded with crystalloids. Group B with normal pregnant females and Group D with Pre‐eclamptic females were Co‐loaded with crystalloids. We compare the HR and BP (SBP and DBP) every 2min for 10 mins and thereafter every 5 min till end of surgery. The umbilical cord blood samples were taken for acid‐base analysis of the neonate and analysis done within 30 mins. The APGAR score of the newborn were recorded at 1min and 5min. All the four groups were comparable in patients age, weight and duration of surgery(p>0.05). The baseline heart rate were comparable between group A and B and between group C and D but intraoperatively both SBP and DBP were significantly higher in group C and D at 5 min, 10 min interval whereas neonatal outcome with respect to APGAR score and acid base profile remained same across all the groups. On the basis of our study we concluded that crystalloid Co‐loading is more effective than Pre‐loading in both normal as well as pre‐eclamptic mothers in preventing spinal anaesthesia induced maternal hypotension and neonatal acidosis during caesarian section but difference is not statistically significant.
How to cite this article:
Neha Sharma, Rajdeep Kour, Neha Sharma, Santosh Devi, Jasmine Chowdhary and Isha Gupta. Comparative Study of Effects of Preloading or Co‐Loading with Crystalloids in Emergency LSCS on Fetal Acid Base Analysis in Normal Vs Preeclamptic Mothers.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.8.68.72
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.8.68.72