Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
The normal concentration of platelets in the blood is between 150 and 400×109/L; their main function is to promote a haemostatic surface in blood vessels (primary haemostasis). Platelets are stored at room temperature, 20‐24o, because below 18oC, their lipid bilayer membrane under goes a phase change which allows the aggregation of surface glycoproteins. PH should be above 6.0 and Platelet count should be less than 5.5×109 in 40‐70 mL plasma, less than 3×1011 in about 300 mL plasma for plateletpheresis. This study aim to evaluate effect of storage on pH, platelet count and swirling score in platelet concentrate. Study was carried for one year from 1 jan 2023 to 1 jan 2024 in the Blood bank and Department of Pathology, Jaipur national university institute for medical science and research centre, jaipur in coordination with Department of paediatrics, JNUIMSRC, jaipur. The quality of platelet product was assessed on day 1, day 3 and day 5 using the following parameters: Swirling ,Volume of the platelet concentrate, Platelet count and pH changes. A total of 50 samples were included in this study and were subjected to assess the in vitro quality by using the parameters such as volume, using Chi Square test. All the samples showed slight changes in swirling, pH, platelet count and WBC count on day 3 and day 5 from the day 1. The changes remained within the limits of recommended quality control parameters. In general, this research found that up to 24 hours has no significant impact on in vitro quality metrics and function.
How to cite this article:
Avadh Kishore, Sumit Kumar, Ajay Kumar Gupta, Naresh N. Rai and Murari Dhanetwal. Evaluation of Changes in PH, Platelet Count and Swirling Score in Platelet Concentrate on Storage.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.209.214
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.209.214