Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Acute Pancreatitis (AP) is a complex clinical condition that poses significant challenges in surgical management. Approximately 20% of patients with AP fail to respond to supportive therapy and develop complications. Accurate early prediction of the severity of AP is crucial for timely intervention and to consider aggressive treatment options. In recent years, various markers have been studied for their ability to stratify the severity of AP, including measures of systemic inflammatory response and direct assessment of pancreatic tissue damage. An ideal marker for AP should appear early, provide reliable and accurate severity staging, and be cost‐effective and easy to measure. The study aimed to evaluate the effectiveness of Haematocrit and Glasgow scoring as early markers for determining the severity of acute pancreatitis. It also sought to compare these markers with CT imaging in evaluating the severity of AP. The study was conducted with in‐patients at the General Surgery Department of Mahatma Gandhi Medical College and Research Institute, Puducherry, from August 2011 to July 2013. Out of 59 patients initially diagnosed with AP, 9 were excluded after normal findings. The remaining patients were assessed using Haematocrit and Glasgow scores, which were then compared with CT grading to evaluate their effectiveness in assessing AP severity. The study found a higher incidence of AP in males (98%), with the most common age group affected being 31‐40 years (32%). Alcoholism was identified as the primary cause in 60% of the patients. The study demonstrated that while serum amylase levels had a significant correlation with CT findings (p = 0.033), Haematocrit showed a stronger correlation (p = 0.007) compared to the Glasgow score. The study concluded that Haematocrit is a more effective marker than the Glasgow score for assessing the severity of acute pancreatitis. It is an easily accessible, low‐cost and reusable test. Despite the value of biochemical markers and scoring systems in evaluating AP, CT scanning remains the definitive tool for diagnosing AP and its complications. Prompt estimation of Serum Amylase and Haematocrit, along with Contrast Enhanced CT, can significantly aid in diagnosing and determining the severity of acute pancreatitis.
How to cite this article:
P. Maharaja and S. Rajendran. Assessment of Severity of Acute Pancreatitis Comparison of Haematocrit and Glasgow Criteria with CT Abdomen.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.322.325
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.322.325