Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Cancer antigen 125 (CA125), a transmembrane glycoprotein detectable and measurable in the blood is found on most malignant ovarian cells. Although it may be a good indicator of ovarian tumors, it is raised in physiologic and non‐malignant conditions. CA125 is still superior and popular to other novel biomarkers in detecting ovarian tumors and an indicator of response to treatment. In this study, various histological types of ovarian neoplasm were evaluated histopathologically along with their respective pre‐operative CA 125 level. All female patients presented with pelvic mass and raised CA125 levels posted for surgery, were included in the study. One hundred and twenty two cases were examined. The data was recorded and appropriate statistical analysis plan was applied. Majority of the patients belonged to 41‐50 years of age group. Serous cystadenoma constituted major proportions (28.7%). Of the 77 women with normal CA‐125 level, 98.7% had benign neoplasm. Fourty Five women had raised CA‐125, of which 17.8%, 37.8% and 44.4% had benign, borderline and malignant neoplasm respectively. Hence concluding, pre‐operative high levels are usually related to clinically advanced ovarian neoplasm, thus helping in stratification of ovarian neoplasm thereby planning the further treatment course.
How to cite this article:
Sneha Bhagat, Papiya Majumdar, Pratyusha Bhattacharjee and Rishav Raj. CA125 and Ovarian Neoplasm, do they Tally in the Rally: Study in Eastern India.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.343.346
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.343.346