Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Evaluation of pulmonary hypertension using computed tomography measurement of pulmonary artery in interstitial lung disease among the patients attending the tertiary care hospital, South India
Runjjala Kiranmai, Pagadala Padmavathi, Boddepalli Manjeera and Muppana Gowthami
Page: 388-393 | Received 28 Jan 2024, Published online: 28 Mar 2024
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Abstract
Aim of this study is to determine how accurately various measures of the PA, as viewed on HRCT, predict right heart catheterization (RHC)-confirmed pulmonary hypertension. Methods: The present study was conducted in the Department of Radiology and 200 patients were included in the study. Patients with a CT scan within 90 days of MRI and RHC were included. In order to meet inclusion criteria, a diagnostic quality CT pulmonary angiogram (CTPA) with a slice thickness of less than 5 mm was required. Results: 100 (50%) of 200 participants in our study had RHC-verified pulmonary hypertension and 25 mmHg mPAP. The pulmonary hypertension group had higher MPAD, RPAD, LPAD, and PA:Ao during both respiratory cycles than the non-hypertensive group. Non-pulmonary hypertension patients had a larger PA angle. The median MPAD in the pulmonary hypertension subgroup was 34.60 mm during inspiration and 34.65 mm during expiration. In contrast, non-pulmonary hypertension patients had a median MPAD of 30.00 mm during inspiration and 30.50 mm during expiration. The inspiratory MPAD and PA:Ao AUCs for RHC-confirmed pulmonary hypertension (Mpap ≥25 mmHg) were 0.741 and 0.750, respectively, for the entire group. The population's diagnostic traits were best when MPAD cut-offs were 32.5 mm and PA:Ao were 0.94. Conclusion: HRCT findings can aid in diagnosing pulmonary hypertension that has been verified by RHC. The sensitivity of MPAD was 29 mm, whereas the specificity of PA:Ao was 1.0. MPAD exhibited higher sensitivity in ILD compared to the overall cohort, while PA:Ao had greater specificity in COPD.
How to cite this article:
Runjjala Kiranmai, Pagadala Padmavathi, Boddepalli Manjeera and Muppana Gowthami. Evaluation of pulmonary hypertension using computed tomography measurement of pulmonary artery in interstitial lung disease among the patients attending the tertiary care hospital, South India.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.388.393
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.388.393