Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Multidrug resistance refers to the ability of microorganisms, to resist multiple antimicrobial drugs. This phenomenon poses a significant challenge in treating infections and can lead to the failure of antibiotic therapies. It often arises due to genetic mutations or the acquisition of resistance genes through horizontal gene transfer. Present study is undertaken to identify the genotypic characterisation of carbapenemase resistant Enterobacteriaceae by the detection of BLA NDM‐1 gene. Polymerase chain reaction is performed for the detection of the resistant gene in 121 carbapenemase producing strains of Enterobacteriaceae. 86% of the strains showed presence of BLA NDM‐1genes. routine screening the hospital acquired strains need to be subjected for the detection of antibiotic resistant genes to prevent the spreading of Multiple drug resistant strains.
How to cite this article:
Satyaram Satapathy, Meet Krishna and Ramanath Karicheri. Molecular Characterisation of Carbapenemase Resistance in Enterobacteriaceae by Detection of BLA NDM‐1 Gene From A Tertiary Care Center.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.475.478
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.475.478