Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Thyroid gland disorders stand as the most prevalent endocrine disorder in India, representing the leading preventable cause of intellectual disability. The absence of a neonatal screening program results in undiagnosed thyroid disorders among Indian children. The objective of this study was to assess the thyroid hormone levels in healthy newborns whose mothers had hypothyroidism during pregnancy. A total of 132 pregnant women were included in the study. The participants were divided into two groups: the Study group, consisting of hypothyroid pregnant women and the Control group. Blood samples were collected from all newborns on day 4 of life for thyroid profile evaluation. Statistical analysis was performed using Microsoft Excel and SPSS software, employing Chi‐square test and student t test to determine significance levels. The findings revealed that majority of newborns in the Study group and in the Control group were appropriate for their gestational age. Notably, there were significant differences in weight for gestational age between the two groups. However, when comparing the thyroid profiles, no significant differences were observed. Thyroid disorders during pregnancy can impact fetal development, potentially leading to neonatal thyroid dysfunction, which may be temporary or permanent. This can contribute to metabolic and cardiovascular complications, emphasizing the importance of monitoring thyroid function during pregnancy.
How to cite this article:
Shashank Tyagi, Ruchita Ranka, Ketan Chaturvedi and Amita Sharma. A Comparative Analysis of Thyroid Hormone Levels in Healthy Newborns from Hypothyroid and Healthy Mothers.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.479.482
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.479.482