Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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The Effect of Intravenous Lignocaine Infusion on Analgesic Requirement During Intra Operative and Post Operative Period in Patients Undergoing Major Surgery Under General Anaesthesia
Shruti M. Shah, Hina R. Gajjar, Sejal D. Shelat, Shrutika Ved, Prarthana H. Pandit and Denika Patel
Page: 491-495 | Received 15 Mar 2024, Published online: 26 Apr 2024
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Abstract
In patients undergoing major surgery under General anaesthesia, adequate analgesia during intra operative and postoperative period is essential for ensuring patient’s comfort and recovery after surgery. This study is sought to determine the effect of intravenous Lignocaine on analgesic requirement during Intra operative and Postoperative period in patients undergoing major surgery under General anaesthesia. The current Prospective Observational study was carried out in 100 patients. Each group had 50 patients. Patients in Group L received Intra operatively: Inj. Lignocaine 2mg/kg ( diluted in 10 ml NS) bolus followed by infusion Inj Lignocaine 2mg/kg/hr and continued for 24 hours postoperatively. Inj. Fentanyl 1mcg/kg as bolus dosage as and when required intra operatively (Increase in MAP/Heart rate >20% of baseline). Post operatively: Inj. Tramadol 100 mg IV as and when patient complains of pain or VAS score >4. Patients in Group C received Intra operatively: bolus dose of IV Normal saline 10 ml followed by infusion for post operatively 24 hours. Inj. fentanyl 1mcg/kg as needed during surgery(Increase in MAP/Heart rate >20% of baseline). Post operatively: Inj. Tramadol 1mg/kg IV +Inj. Ondansetron 0.15mg/kg as and when a patient complains of pain or VAS score >4. Postoperative pain levels were assessed at 1, 2, 4, 8, 12 and 24 hours. The visual analogue scale (VAS) was used to assess postoperative analgesia. Total consumption of fentanyl intra operativelyApril 23, was significantly lessened in Group L. VAS scores at postoperative 1, 2, 4, 8, 12 and 24 hours were statistically significantly lower in Group L than in Group C (p = 0.05) and total intravenous Tramadol consumption in Group L was significantly less than Group C. Intra operative lignocaine infusion decreases overall opioid requirement and postoperative pain intensity in patients undergoing major surgery under General anaesthesia. There was a low incidence of PONV and better patient satisfaction with the lignocaine group. There were no postoperative complications such as light headedness, tinnitus, peri oral numbness and arrhythmia.
How to cite this article:
Shruti M. Shah, Hina R. Gajjar, Sejal D. Shelat, Shrutika Ved, Prarthana H. Pandit and Denika Patel. The Effect of Intravenous Lignocaine Infusion on Analgesic Requirement During Intra Operative and Post Operative Period in Patients Undergoing Major Surgery Under General Anaesthesia.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.491.495
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.491.495