Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Antibiotic Susceptibility Pattern of Bacteria Isolated from Adult Patients with Ventilator Associated Pneumonia (VAP) in Intensive Care Units in a Tertiary Care Hospital
Dr. Rameez Yusuf and Dr. Kaberi Pal
Page: 727-730 | Received 24 Aug 2024, Published online: 23 Sep 2024
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Abstract
Ventilator Associated Pneumonia (VAP) is defined as pneumonia occurring more than 48 hours of mechanical ventilation and not incubating at the time of intubation.VAP is the most frequent Intensive Care Unit (ICU) acquired infection occurring in 9-24% of patients intubated for longer than 48 hours. To assess the clinical and bacteriological profile of VAP, risk factors, prevalence of multidrug-resistant pathogens in VAP cases in ICU setting and to correlate Endotracheal aspirate (ETA) with blood culture in those cases. In this descriptive cross sectional study, 172 patients who were on mechanical ventilation are studied.In this study, positive culture was defined as the presence of more than or equal to 10 000 colony units per milliliter in the Broncho alveolar lavage specimen from patients with ventilator dependent pneumonia. In Acinetobacter baumannii complex, we found that 2 (50%) patients were found to be Sensitive to Amikacin and 2 (50%) patients were found to be resistant to Amikacin. 4(100%) patients were found to be resistant to Ampicillin. 3 (75%) patients were found to be Sensitive to Meropenem and 1(25%) patients were found to be resistant to Meropenem and 1 (25%) patient were found to be Sensitive to Tigecycline and 3(75%) patients were found to be resistant to Tigecycline. In conclusion, the study on antibiotic susceptibility patterns of bacteria isolated from adult patients with ventilator-associated pneumonia (VAP) in intensive care units of a tertiary care hospital highlights significant findings relevant to clinical practice. The results indicate a high prevalence of multidrug-resistant organisms, underscoring the need for stringent infection control measures and the importance of routine surveillance in managing VAP.
How to cite this article:
Dr. Rameez Yusuf and Dr. Kaberi Pal. Antibiotic Susceptibility Pattern of Bacteria Isolated from Adult Patients with Ventilator Associated Pneumonia (VAP) in Intensive Care Units in a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.8.18.727.730
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.8.18.727.730