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International Journal of Tropical Medicine

ISSN: Online 1818-779X
ISSN: Print 1816-3319
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Prevalence of Seronegativity for Rubella IgG Antibodies in Women Between 15‐25 Years of Age: Prospective Observational Study

A.M. Dhivyaa, R.L. Jayavani, Annu Kumari, A. Dhivya, G.R.V. Prasad and Mini P. Singh
Page: 1-6 | Received 10 Oct 2024, Published online: 17 Dec 2024

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https://doi.org/10.36478/10.36478/makijtm.2025.1.1.6

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Abstract

Rubella being a mild infection, rarely causes any complications in childhood, will cause adverse effects during pregnancy ranging from miscarriage to a child born with congenital rubella syndrome. Prevalence of seronegativity for rubella IgG antibodies in women between 15‐25 years of age‐a prospective observational study. A prospective study was conducted in the department of obstetrics and gynecology at PGIMER, Chandigarh. A total of 200 women of between 15‐25 years who attended gynecology OPD for other reasons selected for the study. After obtaining informed consent, their blood samples were collected. The IgG antibody in the serum was estimated by ELISA. Statistical analysis was done using Statistical Package for the Social Sciences (SPSS) version 22.0. Based on the test results, 166(83%) were immune 33 (16.5%) were not immune and 1 (0.5%) had indeterminate result. Evaluation of susceptibility of women in reproductive age to rubella infection is important to setup a strategy for preventing antenatal rubella through vaccination of non‐immune women throughout the country. Through the present study, it can be concluded that screening and vaccination should be targeted at population groups who are at risk including adolescents and women of childbearing age.

How to cite this article:

A.M. Dhivyaa, R.L. Jayavani, Annu Kumari, A. Dhivya, G.R.V. Prasad and Mini P. Singh. Prevalence of Seronegativity for Rubella IgG Antibodies in Women Between 15‐25 Years of Age: Prospective Observational Study.
DOI: https://doi.org/10.36478/10.36478/makijtm.2025.1.1.6
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2025.1.1.6