International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
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Clinico Biochemical Profile of Hepatic Involvement Among Children with Acute Dengue Infection in a Tertiary care Hospital A Record Based Study
Saumyen De, Sandip Kumar Mandal, Abhijit Biswas and Sreetama Saha
Page: 7-10 | Received 15 Nov 2023, Published online: 04 Jan 2024
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Abstract
The dengue virus is a major public health concern that has been more prevalent recently with complex and unusual symptoms. Dengue is known to impact the liver and can cause a variety of symptoms, including fulminant hepatic failure, increased liver enzymes, and hepatomegaly. Objective: to investigate the clinical correlations between liver dysfunction in childhood dengue infection and factors such as severity, clinical features, other laboratory parameters, morbidity and death. The present study was a Descriptive, Retrospective, Record based study. Records was checked and collected of the children admitted with Dengue infection during the period of january 2022 to December 2022. Data collection and analysis was done during Sep‐Oct 2023 after obtaining TAC and IEC clearance. The study was done at department of Paediatric, College of Medicine and Sagore Dutta Hospital, Kolkata, and West Bengal 700058. Total 50 patients were included in this study. In our study, 21 (42%) patients had Probable Dengue (PD) Diagnosis, 22 (44%) patients had Dengue with Warning Signs (D+WS) Diagnosis and 7 (14%) patients had Severe Dengue (SD) Diagnosis. The value of z is 3.3057. The value of p is .00094. The result is significant at p<.05. There have been reports of dengue outbreaks in developing nations like India that have varied degrees of increased hepatic involvement. Early detection of Dengue hepatic dysfunction should help to prevent potentially fatal complications because it is a temporary and reversible condition. This may lessen the morbidity and mortality brought on by dengue fever. Additional research should be done to analyze the role hepato‐protective drugs have in lowering morbidity and mortality rates.
How to cite this article:
Saumyen De, Sandip Kumar Mandal, Abhijit Biswas and Sreetama Saha. Clinico Biochemical Profile of Hepatic Involvement Among Children with Acute Dengue Infection in a
Tertiary care Hospital A Record Based Study.
DOI: https://doi.org/10.36478/10.59218/makijtm.2024.1.7.10
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2024.1.7.10