Journal of Animal and Veterinary Advances
ISSN: Online 1993-601XISSN: Print 1680-5593
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The Differences of Serum IFN-β and Antibodies Concentrations in Chickens at Early and Late ALV-J Infection Stage
Yue Yin, Xi Lan, Kai Tian, Tian-Jie Li, Qing Zhu, Yi-Ping Liu, Xiao-Ling Zhao, Hua-Dong Yin, Yao-Dong Hu and Yan Wang
Page: 930-936 | Received 21 Sep 2022, Published online: 21 Sep 2022
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Abstract
Interferon-β (IFN-β) and immunoglobulin M (IgM), immunoglobulin G (IgG) are essential in anti-retrovirus progress. ALV-J is a kind of ubiquitous retrovirus in chicken. To investigate whether natural Avian Leukosis Virus strain J (ALV-J) infection has effect on the concentrations of serum IFN-β, IgM and IgG, two important time points after hatching, 3 and 18 weeks age which represent the early and late stages of ALV-J infection, respectively were decided to study. The results reveal that the serum IFN-β, IgM and IgG increase at the early stage of ALV-J infection while decrease at the late stage compared with the control chickens which indicate that ALV-J infection boosts the immune response and up-regulates IFN-β and antibody while long-term infection suppresses immune function and down-regulates IFN-β and antibody.
How to cite this article:
Yue Yin, Xi Lan, Kai Tian, Tian-Jie Li, Qing Zhu, Yi-Ping Liu, Xiao-Ling Zhao, Hua-Dong Yin, Yao-Dong Hu and Yan Wang. The Differences of Serum IFN-β and Antibodies Concentrations in Chickens at Early and Late ALV-J Infection Stage.
DOI: https://doi.org/10.36478/javaa.2014.930.936
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2014.930.936